Officers were called to the Greenaker home around 9pm on Sunday after reports of shots being fired at the home.
Before the car took off, three bullets were fired at the house, which was captured on CCTV.
No one was injured and no other property was damaged.
Police believe it was a premeditated and targeted attack after the car was pulled into the street at 6.25pm and waited for two-and-a-half hours.
The property is home to members of the Scuff family.
Brothers Bilal and Mohammed were convicted of gang rapes in Sydney’s south-west in the 1990s.
Bilal remains in prison and Muhammad lives in the Greenacre property on strict parole.
A younger brother, Hadi, who is not involved in crime, also lives at home.
Detectives are now investigating whether the target of the shooting was Hadiya, 22, who was in court last week for possessing a firearm in public.
Residents were shocked by the heinous crime.
“I looked over and was like, ‘Oh my god, we’ve got a crime scene, the police are here,'” said local Mary Doges.
“I thought someone must have been shot.
“It worries us, but we have to live with it.”
Forensic crews spent the night on the street searching for evidence, and detectives returned today, knocking on doors for clues that could lead to a closer look at the gunman.